CURE IN CANCER

"Any intelligent fool can make things bigger and more complex. It takes a lot of genius and a lot of courage to move in the opposite direction." – Albert EISTEIN

Tumor Laterality – Left or Right ?

Tumor Laterality – Left or Right ?

Mammary glands can be left or right different. But most of the time when we look at them they are almost identical. Almost..but at the cellular and molecular level there are many differences. There are almost 160 different genes that are left/right different.

Left Side – Cellular content – Mammary stem cells twice as many as right side. These are the cells that get mutated and that is why more tumors form on the left side. More spheres (Stem cells) on the left side and also the spheres were smaller.

Right Side – Cellular content – Mammary stem cells twice as low as left side. These are the cells that get mutated and that is why less tumors form on the left side. More spheres (Stem cells) on the left side and also the spheres were smaller.

Left (Gene Expression Profile)Right (Gene Expression Profile)
55% of tumors for the left side45 % of tumors form on the right side
Survival rate is moreSurvival rate is less
More stem cellsLess stem cells
Smaller sphereLarger spheres
Lapatanib responded wellLapatanib did not respond well

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